Electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC): Finding the optimal electrical potential

Background: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a therapy option for patients with peritoneal metastases. During PIPAC, high-pressure injector delivers the drugs through nebulizer into cavity. However, gravity typically causes inhomogeneous droplet distribution in space and may be overcome by addition of an electrostatic force, resulting precipitation PIPAC (ePIPAC). Our goal was to find optimal electrical potential ePIPAC means vitro experiments numerical modeling.